diff --git a/docs/demos/portal.md b/docs/demos/portal.md
new file mode 100644
index 00000000..5611bd1d
--- /dev/null
+++ b/docs/demos/portal.md
@@ -0,0 +1,8 @@
+---
+title: Portal
+nav:
+  title: Demo
+  path: /demo
+---
+
+<code src="../examples/portal.tsx"></code>
diff --git a/docs/examples/portal.tsx b/docs/examples/portal.tsx
new file mode 100644
index 00000000..a1b66576
--- /dev/null
+++ b/docs/examples/portal.tsx
@@ -0,0 +1,110 @@
+/* eslint no-console:0 */
+
+import Trigger from 'rc-trigger';
+import React from 'react';
+import { createPortal } from 'react-dom';
+import '../../assets/index.less';
+
+const builtinPlacements = {
+  left: {
+    points: ['cr', 'cl'],
+  },
+  right: {
+    points: ['cl', 'cr'],
+  },
+  top: {
+    points: ['bc', 'tc'],
+  },
+  bottom: {
+    points: ['tc', 'bc'],
+  },
+  topLeft: {
+    points: ['bl', 'tl'],
+  },
+  topRight: {
+    points: ['br', 'tr'],
+  },
+  bottomRight: {
+    points: ['tr', 'br'],
+  },
+  bottomLeft: {
+    points: ['tl', 'bl'],
+  },
+};
+
+const popupBorderStyle = {
+  border: '1px solid red',
+  padding: 10,
+  background: 'rgba(255, 0, 0, 0.1)',
+};
+
+const PortalPopup = () =>
+  createPortal(
+    <div
+      style={popupBorderStyle}
+      onMouseDown={(e) => {
+        console.log('Portal Down', e);
+        e.stopPropagation();
+        e.preventDefault();
+      }}
+    >
+      i am a portal element
+    </div>,
+    document.body,
+  );
+
+const Test = () => {
+  const buttonRef = React.useRef<HTMLButtonElement>(null);
+  React.useEffect(() => {
+    const button = buttonRef.current;
+    if (button) {
+      button.addEventListener('mousedown', (e) => {
+        console.log('button natives down');
+        e.stopPropagation();
+        e.preventDefault();
+      });
+    }
+  }, []);
+
+  return (
+    <div
+      style={{
+        padding: 100,
+        display: 'flex',
+        flexDirection: 'column',
+        alignItems: 'flex-start',
+        gap: 100,
+      }}
+    >
+      <Trigger
+        popupPlacement="right"
+        action={['click']}
+        builtinPlacements={builtinPlacements}
+        popup={
+          <div style={popupBorderStyle}>
+            i am a click popup
+            <PortalPopup />
+          </div>
+        }
+        onPopupVisibleChange={(visible) => {
+          console.log('visible change:', visible);
+        }}
+      >
+        <button>Click Me</button>
+      </Trigger>
+
+      <button
+        onMouseDown={(e) => {
+          console.log('button down');
+          e.stopPropagation();
+          e.preventDefault();
+        }}
+      >
+        Stop Pop & Prevent Default
+      </button>
+      <button ref={buttonRef}>Native Stop Pop & Prevent Default</button>
+    </div>
+  );
+};
+
+export default Test;
diff --git a/src/Popup/index.tsx b/src/Popup/index.tsx
index e5d64d42..a1052ab2 100644
--- a/src/Popup/index.tsx
+++ b/src/Popup/index.tsx
@@ -20,6 +20,7 @@ export interface PopupProps {
   onMouseEnter?: React.MouseEventHandler<HTMLDivElement>;
   onMouseLeave?: React.MouseEventHandler<HTMLDivElement>;
   onPointerEnter?: React.MouseEventHandler<HTMLDivElement>;
+  onMouseDownCapture?: React.MouseEventHandler<HTMLDivElement>;
   zIndex?: number;
 
   mask?: boolean;
@@ -105,6 +106,7 @@ const Popup = React.forwardRef<HTMLDivElement, PopupProps>((props, ref) => {
     onMouseEnter,
     onMouseLeave,
     onPointerEnter,
+    onMouseDownCapture,
 
     ready,
     offsetX,
@@ -255,6 +257,7 @@ const Popup = React.forwardRef<HTMLDivElement, PopupProps>((props, ref) => {
                     onMouseLeave={onMouseLeave}
                     onPointerEnter={onPointerEnter}
                     onClick={onClick}
+                    onMouseDownCapture={onMouseDownCapture}
                   >
                     {arrow && (
                       <Arrow
diff --git a/src/index.tsx b/src/index.tsx
index dce5f96e..7a85dc9d 100644
--- a/src/index.tsx
+++ b/src/index.tsx
@@ -381,7 +381,9 @@ export function generateTrigger(
       React.useState<VoidFunction>(null);
 
     // =========================== Align ============================
-    const [mousePos, setMousePos] = React.useState<[x: number, y: number] | null>(null);
+    const [mousePos, setMousePos] = React.useState<
+      [x: number, y: number] | null
+    >(null);
 
     const setMousePosByEvent = (
       event: Pick<React.MouseEvent, 'clientX' | 'clientY'>,
@@ -720,6 +722,14 @@ export function generateTrigger(
             fresh={fresh}
             // Click
             onClick={onPopupClick}
+            onMouseDownCapture={() => {
+              // Additional check for click to hide
+              // Since `createPortal` will not included in the popup element
+              // So we use capture to handle this
+              if (clickToHide) {
+                triggerOpen(true);
+              }
+            }}
             // Mask
             mask={mask}
             // Motion
diff --git a/tests/basic.test.jsx b/tests/basic.test.jsx
index aa4e87d4..e5eb0aa3 100644
--- a/tests/basic.test.jsx
+++ b/tests/basic.test.jsx
@@ -3,7 +3,7 @@
 import { act, cleanup, fireEvent, render } from '@testing-library/react';
 import { spyElementPrototypes } from 'rc-util/lib/test/domHook';
 import React, { StrictMode, createRef } from 'react';
-import ReactDOM from 'react-dom';
+import ReactDOM, { createPortal } from 'react-dom';
 import Trigger from '../src';
 import { awaitFakeTimer, placementAlignMap } from './util';
 
@@ -107,7 +107,7 @@ describe('Trigger.Basic', () => {
       expect(document.querySelector('.x-content').textContent).toBe('tooltip2');
 
       trigger(container, '.target');
-      expect(isPopupHidden).toBeTruthy();
+      expect(isPopupHidden()).toBeTruthy();
     });
 
     it('click works with function', () => {
@@ -1198,4 +1198,35 @@ describe('Trigger.Basic', () => {
     trigger(container, '.target');
     expect(document.querySelector('.x-content').textContent).toBe('false');
   });
+
+  it('createPortal should not close', async () => {
+    const Portal = () =>
+      createPortal(<div className="portal" />, document.body);
+
+    const Demo = () => {
+      return (
+        <>
+          <Trigger action="click" popup={<Portal />}>
+            <div className="target" />
+          </Trigger>
+          <div className="outer" />
+        </>
+      );
+    };
+
+    const { container } = render(<Demo />);
+    fireEvent.click(container.querySelector('.target'));
+    await awaitFakeTimer();
+    expect(isPopupHidden()).toBeFalsy();
+
+    // Click portal should not close
+    fireEvent.click(document.querySelector('.portal'));
+    await awaitFakeTimer();
+    expect(isPopupHidden()).toBeFalsy();
+
+    // Click outside to close
+    fireEvent.mouseDown(container.querySelector('.outer'));
+    await awaitFakeTimer();
+    expect(isPopupHidden()).toBeTruthy();
+  });
 });