This is a tutorial and brief overview of different approaches to infer or adjust for cell proportions using DNA-methylation data inferred from peripheral blood.
Download the example data set:
(2) Click on “Download”. This will download a file by the name FaSTLMM.Py.102.zip.
(3) Unzip the file and the example data can be found in …\FaSTLMM.Py.102\FastLmm.Py\doc\FastLmm-EWASher\demo, by the name
– input_data.txt ( 27k DNA-methylation data on 204 subjects)
– input_phenotype.txt (cancer status of 204 subjects)
– covariates.txt ( other covariates related to 204 subjects)