This repository contains the source data and matching forest plots for an open meta-analysis of Vitamin D supplementation for the prevention of fractures.
This meta-analysis suggests that vitamin D supplementation is associated with a reduction in fractures when given in effective doses (see Figure). Effective is defined as a dose that raises the serum level of vitamin D by 20 nmol/L (8 ng/mL) and achieves a final level of at least 60 nmol/L (24 ng/mL). See the clinical summary for more detail. The complete review is in development for peer review and journal publication.
Figure. All trials subgrouped by effective or inneffective dose of Vitamin D.