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Merge pull request #35 from malariagen/GH32-add-ag-cohorts-20240924
Add Ag cohorts analysis 20240924
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--- | ||
layout: post | ||
title: "Ag3 cohorts analysis version 20240924" | ||
tags: data | ||
--- | ||
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A new cohorts analysis version `20240924` has been released for the | ||
Ag3 data resource. This is now the default cohorts analysis version | ||
when using the `malariagen_data` [Ag3 | ||
API](https://malariagen.github.io/malariagen-data-python/latest/Ag3.html). This | ||
cohorts analysis will be available for datasets up to and including Ag3.13. | ||
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Please note that the new cohorts analysis may change the values of | ||
sample metadata columns including `taxon`, `admin1_iso`, | ||
`admin1_name`, `admin2_name`, and derived columns beginning `cohorts_` | ||
relative to previous cohorts analysis versions. | ||
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To pin this cohorts analysis when accessing data: | ||
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{% highlight python %} | ||
import malariagen_data | ||
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ag3 = malariagen_data.Ag3( | ||
cohorts_analysis="20240924", | ||
) | ||
{% endhighlight %} | ||
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This new version introduces some key changes: | ||
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- Samples previously labeled as `gcx1` in the `taxon` field have been renamed to `bissau`: | ||
- `gcx` (`gambiae complex cryptic taxa`) labels serve as placeholders for groups outside our usual taxonomic assignment | ||
- Following [Caputo et al. (2024)](https://malariagen.github.io/vobs-updates/2024/09/10/caputo.html), the `gcx1` group has been renamed to `Bissau molecular form` | ||
- 291 samples previously assigned as `gcx1`, are now labeled as `bissau`. | ||
- 5 previously `unassigned` samples are also relabeled as `bissau`. | ||
- Cohort names have been updated, e.g. `GM-M_gcx1_2019` is now `GM-M_biss_2019` | ||
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- 36 previously `unassigned` samples have been reclassified as: 32 `melas`, 2`gambiae`, 1 `fontenillei`, 1 `arabiensis`. | ||
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- A location metadata error affecting the administrative region (level 1) of 119 samples has been corrected: | ||
- `admin1_iso` updated from `UG-E` to `KE-04` | ||
- `admin1_name` updated from `Eastern Region` to `Busia` | ||
- Cohort names have been updated, e.g. `UG-E_arab_2013` has now been relabeled to `KE-04_arab_2013` | ||
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If you need to access the previous version of the cohorts analysis, you can pin it using the code in [here](https://malariagen.github.io/vobs-updates/2024/07/24/ag3-cohorts-v20240717.html). |